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ERRα antagonist-1
CAS No. 1072145-33-5
ERRα antagonist-1( ERR+/- antagonist-1 | ERRa antagonist-1 )
Catalog No. M26207 CAS No. 1072145-33-5
ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 61 | Get Quote |
|
| 10MG | 110 | Get Quote |
|
| 25MG | 222 | Get Quote |
|
| 50MG | 335 | Get Quote |
|
| 100MG | 494 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameERRα antagonist-1
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NoteResearch use only, not for human use.
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Brief DescriptionERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist.
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DescriptionERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively.
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In Vitro——
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In Vivo——
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SynonymsERR+/- antagonist-1 | ERRa antagonist-1
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1072145-33-5
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Formula Weight377.52
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Molecular FormulaC21H19N3S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (66.22 mM)
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SMILESC1CN=C(S1)N1CCS\C1=N/C1c2ccccc2C=Cc2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shi S, Liu Y, Wu J, Li Z, Zhao Y, Zhong D, Zeng F. Comparative bioavailability and tolerability of a single 20-mg dose of two fluoxetine hydrochloride dispersible tablet formulations in fasting, healthy Chinese male volunteers:an open-label, randomized-sequence, two-period crossover study. Clin Ther. 2010 Oct;32(11):1977-86.
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